如何把握胃癌手术中消化道重建方式的临床研究

How to master the clinical study on digestive tract reconstruction in gastric cancer surgery

消化道重建是胃癌外科手术中的重要环节。消化道重建方式的选择与消化道重建新术式的应用是胃癌消化道重建领域研究中的重要议题。消化道重建方式的临床研究需通过科学的研究设计与实施,综合评估重建方式对外科安全性结局、远期生存结局、生活质量的近远期变化、内镜下黏膜变化以及术后患者营养状态等观察指标的影响。此外,卫生经济学指标分析也是消化道重建研究中需要考量的指标之一。依据患者个体化特征选择合适的消化道重建方式可能是今后消化道重建研究领域的重要方向。

Digestive tract reconstruction is extremely important during gastric cancer surgery,which is related to long-tern quality of life of patients.The selection of reconstruction methods and the application of reconstruction techniques are major topics in the field of reconstruction-related study of gastric cancer surgery.The clinical research on digestive tract reconstruction needs to be designed and implemented scientifically to comprehensively evaluate the impact of reconstruction methods on surgical safety,long-term survival outcomes,short-and long-term changes in quality of life,endoscopic mucosal changes and postoperative nutritional status.In addition,health economic analysis is also important and should be considered in reconstruction-related studies.In brief,selection of appropriate gastrointestinal reconstruction methods based on individual characteristics of each gastric cancer patients may be an important direction of clinical trials in the future.