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四肢创伤患者血清纤维蛋白溶解酶原激活物抑制剂⁃1、血清组织因子、血清抗凝血酶水平变化及临床意义 被引量:2

Changes and Clinical Significance of Serum Plasminogen Activator Inhibitor-1,Tissue Factor and Antithrombin Levels in Patients with Limb Trauma
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摘要 目的探讨四肢创伤患者血清纤维蛋白溶解酶原激活物抑制剂-1(PAI-1)、血清组织因子(TF)、血清抗凝血酶(AT)水平变化及临床意义。方法以82例四肢创伤患者为对象,以同期82例健康人为对照组。检测PAI-1、TF、AT水平,分析其与患者病情的关系。结果观察组PAI-1、TF水平低于对照组,AT水平高于对照组(P<0.05)。轻度组伤后1 d PAI-1水平低于重度组(P<0.05);伤后1 d、7 d TF水平低于重度组,AT水平高于对照组(P<0.05)。结论四肢创伤患者PAI-1、TF水平升高,AT水平降低,其水平可反映创伤的严重程度。
作者 张永和 曹文 ZHANG Yong-he;CAO Wen(Department of Traumatology and Lower Limbs,Xi’an Honghui Hospital,Xi’an,710054,China;Department of Emergency,Shaanxi Rehabilitation Hospital,Xi’an,710065,China)
出处 《血栓与止血学》 CAS 2022年第3期641-642,共2页 Chinese Journal of Thrombosis and Hemostasis
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