理气通腑针法对胃癌根治术患者术后胃肠功能恢复的影响

Effect of Acupuncture for Regulating Qi and Unblocking Fu-Organs on Postoperative Gastrointestinal Function Recovery of Patients After Radical Gastrectomy for Gastric Cancer

目的:观察理气通腑针法对胃癌根治术患者术后胃肠功能恢复的影响。方法:选取胃癌根治性手术患者 80 例,根据随机数字表法分为试验组和对照组各 40 例。对照组采用常规治疗方案,试验组在对照组的基础上进行理气通腑针法治疗。比较2 组术后基本恢复情况及治疗前后中医证候评分、胃泌素 (GAS)、胃动素 (MTL)、血管活性肠肽 (VIP)、外周 T 细胞亚群 (CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)) 及自然杀伤细胞 (NK) 水平。结果:治疗后,试验组首次进食、排气、排便时间及住院时间均较对照组显著缩短 (P<0.05)。治疗后,2 组中医证候评分、GAS 水平均较治疗前显著降低 (P<0.05),且试验组上述指标均低于对照组 (P<0.05)。治疗后,2 组 MTL、VIP、CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)及 NK 细胞水平均较治疗前显著升高 (P<0.05),且试验组各项指标均高于对照组 (P<0.05)。2 组均无严重不良反应。结论:理气通腑针法对胃癌根治术患者术后胃肠功能恢复疗效显著,能够有效缓解患者临床症状,调节胃肠激素及机体免疫功能,促进胃肠道功能恢复。

Objective:To observe the effect of acupuncture for regulating qi and unblocking fu- organs on the postoperative gastrointestinal function recovery of patients after radical gastrectomy for gastric cancer.Methods:A total of80 patients after radical gastrectomy for gastric cancer were selected and divided into the control group and the experiment group according to random number table method,with 40 cases in each group.The control group was treated with conventional treatment,and the experiment group was additionally treated with acupuncture for regulating qi and unblocking fu-organs based on the treatment of the control group.The basic recovery after surgery and the changes in Chinese medicine syndrome scores and levels of gastrin(GAS),motilin(MTL),vasoactive intestinal peptide(VIP),peripheral T cell subsets(CD3^(+),CD4^(+),CD4^(+)/CD8^(+)) and natural killer cells(NK) before and after treatment were compared between the two groups.Results:After treatment,the time of first feeding,first farting,first defecation and hospital stay in the experiment group were significantly shorter than those in the control group(P<0.05).After treatment,the Chinese medicine syndrome scores and GAS levels in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the above two indexes in the experiment group were lower than those in the control group(P<0.05).After treatment,the levels of MTL,VIP,CD3^(+),CD4^(+),CD4^(+)/CD8^(+ )and NK cells in both groups were significantly increased when compared with those before treatment(P<0.05),and the above levels in the experiment group were higher than those in the control group(P<0.05);there were no serious adverse reactions in both groups.Conclusion:Acupuncture for regulating qi and unblocking fu- organs has a significant effect on the gastrointestinal function recovery of patients after radical gastrectomy for gastric cancer,which can effectively relieve clinical symptoms,regulate gastrointestinal hormones and immune function,and promote gastrointestinal function recovery.