舒敏专家导入医用修复敷料在颜面再发性皮炎患者中的应用效果

Application effect of shumin expert imported medical repair dressing in patients with facial recurrent dermatitis

目的探讨舒敏专家导入医用修复敷料在颜面再发性皮炎患者中的应用效果。方法选取2019年7月至2021年7月就诊于江西省皮肤病专科医院的92例颜面再发性皮炎患者为研究对象,按随机数字表分为对照组和治疗组,每组各46例。对照组口服枸地氯雷他定片,外用医院自制的维生素E乳膏;治疗组口服枸地氯雷他定片,配合舒敏专家导入医用修复敷料,两组连续治疗4周。比较两组的临床治疗效果、主要皮损症状评分,检测皮肤生物学指标[角质层含水量、经皮水流失(TEWL)、油脂含量、红斑量]、血清中免疫球蛋白E(IgE)、外周血嗜酸性粒细胞(EOS)含量。结果治疗组的总有效率高于对照组,差异有统计学意义(P<0.05);治疗后治疗组患者的灼热、痒痛、紧绷感、红斑评分均低于对照组,差异有统计学意义(P<0.05);治疗后治疗组TEWL、红斑量低于对照组,油脂含量、角质层含水量高于对照组,外周血中EOS、IgE低于对照组,差异有统计学意义(P<0.05);两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论舒敏专家导入医用修复敷料可改善皮肤屏障功能,安全有效,值得推广。

Objective To explore the application effect of shumin expert imported medical repair dressing in patients with facial recurrent dermatitis.Methods A total of 92 patients with recurrent facial dermatitis admitted to Jiangxi Provincial Hospital of Dermatology from July 2019 to July 2021 were selected as the research subjects,and were divided into control group and treatment group according to random number table,with 46 cases in each group.The control group was treated with oral Medloratadine Tablets and Vitamin E Cream made by the hospital.The treatment group oral Medloratadine Tablets,with shumin expert imported medical repair dressing.Both groups were treated for 4 weeks.The clinical effect,main skin lesion symptom scores,skin biological indexes(cuticle moisture content,transdermal water loss[TEWL],oil content,erythema volume),serum immunoglobulin E(IgE)and peripheral blood eosinophils(EOS)were compared between the two groups.Results The total effective rate of treatment group was higher than that of control group,the difference was statistically significant(P<0.05).After treatment,the scores of burning,itching,tension and erythema in treatment group were lower than those in control group,the differences were statistically significant(P<0.05).After treatment,the amount of TEWL and erythema in the treatment group was lower than that in the control group,the content of oil and corneum water were higher than that in the control group,and the EOS and IgE in peripheral blood were lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Shumin expert imported medical repair dressing can improve the skin barrier function,safe and effective,worthy of promotion.