长链非编码RNA LINC01614在恶性肿瘤中作用的研究进展

Research progress on the role of long non-coding RNA LINC01614 in malignant tumors

长链非编码RNA在恶性肿瘤组织中差异表达已被大量研究证实。长链非编码RNA LINC01614在多种恶性肿瘤组织中均呈高表达,且与肿瘤患者的临床病理指标密切相关,并通过多种机制影响肿瘤的发生与发展,其被认为可能具有作为诊断或判断肿瘤预后生物标志物以及有效治疗靶点的潜力。该文对LINC01614在恶性肿瘤中的作用及其机制进行综述。

Differential expression of long non-coding RNA in malignant tumor tissues has been confirmed by a large number of studies.Long non-coding RNA LINC01614 is highly expressed in a variety of malignant tumor tissues,which is closely related to the clinicopathological indicators of tumor patients and affects the occurrence and development of tumors through multiple mechanisms.Therefore,LINC01614 is considered to have the potential as a biomarker for diagnosis or prognosis evaluation and an effective therapeutic target of tumors.This article reviews research progress on the role and mechanism of LINC01614 in malignant tumors.