移动医疗在胰腺癌患者全程管理中应用的研究

Study on the application of mobile health in whole course management of pancreatic cancer

目的分析通过移动终端对胰腺癌患者术后全程管理的可行性和有效性。方法回顾性分析2015年1月至2021年1月收治的114例行胰腺癌根治性手术切除患者的临床资料,根据术后是否使用移动终端设备对患者进行全程管理将病例分为干预组(n=64例)和对照组(n=50例)。采用SPSS22.0软件进行统计学分析,计量资料采用(x±s)进行描述,独立样本t检验;计数资料以频数、率(%)及中位数(四分位数间距)进行描述,采用卡方检验。K-M法进行术后生存分析。P<0.05为差异有统计学意义。结果单因素统计分析结果提示千预组的随访率、辅助治疗完成率较对照组显著升高,差异有统计学意义(P<0.05)。将完成随访的99例患者行K-M法术后生存分析结果显示,干预组中位无瘤生存时间16个月,中位总生存时间21个月;对照组中位无瘤生存时间10.5个月,中位总生存时间19.5个月,于预组的无瘤生存率高于对照组,差异具有统计学意义(P<0.05),干预组总生存率略高于对照组,差异无统计学意义(P=0.128)。结论通过移动终端对胰腺癌患者术后进行全程管理,可显著提高患者随访率、辅助治疗完成率和无瘤生存率,值得推广。

Objective To analyze the feasibility and effectiveness of the whole postoperative management of pancreatic cancer patients through mobile terminals.Methods Retrospective analysis the clinical data of 114 patients with radical resection of pancreatic cancer from January 2015 to January 2021.Patients were divided into the intervention group(n=64 cases)and control group(n=50 cases)according to whether mobile terminal devices were used for the whole postoperative management of patients.SPSS 22.0 software was used for statistical analysis.Measurement data were expressed by(x±s),Independent sample t test.Counting data were described by frequency,rate(%)and median(quadrant spacing)using chi-square test.K-M method was used for postoperative survival analysis,and P<0.05 was considered statistically significant.Results Univariate statistical analysis showed that the follow-up rate and adjuvant therapy completion rate in the intervention group were significantly higher than the control group,with statistically significant differences(P<0.05).The survival analysis results of 99 patients who completed the follow-up after K-M spell showed that the median tumor-free survival time of the intervention group was 16 months,and the median overall survival time was 21 months,while in the control group,the median disease-free survival time was 10.5 months,and the median overall survival time was 19.5 months.The disease-free survival rate of the intervention group was higher than that of the control group,with statistically significant difference(P<0.05),while the overall survival rate of the intervention group was slightly higher than that of the control group,with no statistically significant difference(P=0.128).Conclusion The whole-course management of pancreatic cancer patients through mobile terminals can significantly improve the follow-up rate,adjuvant therapy completion rate and disease-free survival rate,which is worthy of promotion.