神经酰胺在心血管疾病中的研究进展

Research progress of ceramide in cardiovascular diseases

神经酰胺是一类功能复杂的鞘脂,作为第二信使参与细胞生长、分化、应激反应、炎症信号传导和凋亡等过程。近年众多的研究表明,神经酰胺与冠心病、心力衰竭、房颤、高血压等心血管疾病的发生和风险预测有着密切关系。本文就神经酰胺在心血管疾病中的相关研究进展进行概述。

Ceramide is a kind of sphingolipid with complex function,which is involved in cell growth,differentiation,stress response,inflammatory signal transduction and apoptosis as a second messenger.In recent years,many studies have shown that it is closely related to the occurrence and risk prediction of cardiovascular diseases such as coronary heart disease,heart failure,atrial fibrillation,hypertension and so on.In this paper,the related research progress is summarized.