摘要
泰国属恶性疟流行高发地区,随着抗疟药物长期使用,恶性疟原虫对氯喹、奎宁、甲氟喹、青蒿素等常见抗疟药物产生耐药性。本文对泰国恶性疟原虫药物抗性基因研究进展进行综述,为该国消除疟疾有效对策及措施的制定提供参考。
Thailand is an area with the high prevalence of Plasmodium falciparum,and as antimalarial drugs had been widely used for a long time,such as chloroquine,quinine,mefloquine,artemisinin,resulting in the resistance of P.falciparum to above common antimalarial drugs.This paper reviewed the research progress of drug resistance genes of P.falciparum in Thailand,providing the reference for the formulation of effective strategies and measures to eliminate malaria in the country.
作者
周友华
吴艳琴
周红宁
ZHOU You-hua;WU Yan-qin;ZHOU Hong-ning(College of Public Health,Kunming Medical University,Kunming 650000,China;Yunnan Provincial Key Laboratory of Vector-borne Diseases Control and Research & Yunnan Innovative Team of Key Techniques for Vector Borne Disease Control and Prevention (Developing) of Yunnan Institute of Parasitic Diseases)
出处
《中国病原生物学杂志》
CSCD
北大核心
2022年第3期367-371,共5页
Journal of Pathogen Biology
基金
云南省重点研发计划项目(No.202103AQ100001)
澜湄合作专项基金项目(No.2020399)。
关键词
恶性疟原虫
药物抗性基因
泰国
综述
Plasmodium falciparum
drug resistance gene
thailand
review
