摘要
PI3K/Akt/mTOR信号通路与细胞生长的调控密切相关,参与牛脂肪细胞、牛乳腺上皮细胞以及牛卵母细胞等生成发育过程;间接调控炎症因子及代谢过程等方面。文章综述PI3K/Akt/mTOR信号通路的组成成分、作用机制和对不同细胞生长影响,并对其具体作用进行归纳与总结,以期为后续研究家畜细胞生长提供参考。
The PI3K/Akt/mTOR signaling pathway are closely related to the regulation of cell growth,which can be a pivotal part that participates in production and development of bovine adipocytes,bovine mammary epithelial cells and bovine oocytes,can also be a participant,indirectly regulating inflammatory factors,metabolic processes,et al.The paper reviews the components,mechanism and effect on growth of different cells of PI3K/Akt/mTOR signal pathway,to provide reference for the follow-up study on how livestock cell growth.
作者
周乐
常晨城
王宇
满达
石彩霞
张文广
ZHOU Le;CHANG Chen-cheng;WANG Yu;MAN Da;SHI Cai-xia;ZHANG Wen-guang
出处
《饲料研究》
CAS
北大核心
2022年第9期138-142,共5页
Feed Research
基金
内蒙古自治区自然科学基金项目(项目编号:2021ZD05)
内蒙古自治区科技重大专项课题(项目编号:2021ZD0009)。