肠道菌群与子宫内膜异位症发病关系的研究进展

Research Progress in Relationship between Intestinal Flora and Endometriosis

子宫内膜异位症(EMS)是一种常见的妇科慢性炎症性疾病,具有恶性肿瘤的特征,严重影响患者的生活质量和心理健康。目前,EMS的具体发病机制尚未明确,可能与体内性激素失衡、免疫炎症刺激下的异位增生以及基于肿瘤特性的侵袭逃逸等密切相关。随着对肠道菌群研究的深入,其与EMS的关系越来越受到人们的关注。肠道菌群参与EMS的具体途径和机制可能涉及雌激素、免疫炎症、肿瘤特性等环节。因此,未来通过多种方式调节肠道菌群失常可以为EMS患者的治疗提供帮助。

Endometriosis(EMS)is a common chronic gynecologic inflammatory disease with the characteristics of malignant tumors,which seriously affects the quality of life and mental health of the patients.At present,the specific pathogenesis of EMS is not yet clear,which may be closely related to the imbalance of sexual hormones in the body,ectopic hyperplasia stimulated by immune inflammation,and invasion and escape based on tumor characteristics.With the in-depth study of intestinal flora,its relationship with EMS has attracted more and more attention.The specific pathways and mechanisms of intestinal flora participating in EMS may involve estrogen,immune inflammation and tumor characteristics.Therefore,in the future,regulating intestinal flora disorders in various ways can provide help for the treatment of EMS patients.