超觉静坐训练联合麦粒灸治疗轻中度产后抑郁症的临床研究

Clinical study of transcendental meditation training combined with grain moxibustion in treatment of mild to moderate postpartum depression

目的探究在轻中度产后抑郁症患者中采用超觉静坐训练联合麦粒灸治疗的临床应用效果。方法选择86例轻中度产后抑郁症患者,通过抽签法将其分为观察组(n=43)和对照组(n=43)。对照组患者实施西药、心理基础治疗,观察组患者在对照组基础上实施超觉静坐训练联合麦粒灸治疗。比较两组患者干预前与干预8周后的血清5-羟色胺(5-HT)、多巴胺(DA)、雌二醇(E2)、促黄体生成素(LH)水平、爱丁堡产后抑郁量表(EPDS)、匹兹堡睡眠质量指数量表(PSQI)评分以及治疗有效率。结果干预前,两组患者的血清5-HT、DA、E2、LH水平、EPDS评分以及PSQI评分比较,差异均无统计学意义(t分别=0.05、1.24、0.20、0.38、0.23、0.65,P均>0.05)。干预8周后,两组患者的血清5-HT、DA、E2、LH水平高于对照组,EPDS、PSQI评分低于对照组(t分别=6.75、8.37、2.74、9.65、5.73、4.04,P均<0.05);观察组治疗有效率高于对照组(χ^(2)=4.44,P<0.05)。结论在轻中度产后抑郁症患者中采用超觉静坐训练联合麦粒灸治疗可改善患者血清5-HT、DA、E2、LH水平,缓解抑郁情绪,提高睡眠质量与临床疗效。

Objective To explore the clinical effect of transcendental meditation training combined with grain moxibustion on mild to moderate postpartum depression.Methods A total of 86 patients with mild to moderate postpartum depression were selected and divided into observation group(n=43)and control group(n=43)by drawing lots.The patients in the control group were treated with western medicine and psychological basic treatment,and the patients in the observation group were treated with transcendental meditation training combined with grain moxibustion on the basis of the control group.The levels of serum serotonin(5-HT),dopamine(DA),estradiol(E2),luteinizing hormone(LH),and Edinburgh postpartum depression scale(EPDS),Pittsburgh sleep quality index(PSQI)score,and treatment effective rate were compared between the two groups before intervention and 8 weeks after intervention.Results Before intervention,there was no significant difference in serum 5-HT,DA,E2,LH levels,EPDS score,and PSQI score between the two groups(t=0.05,1.24,0.20,0.38,0.23,0.65,P>0.05).After 8 weeks of intervention,the serum levels of 5-HT,DA,E2,and LH in the observation group were higher than those in the control group,and the EPDS and PSQI scores were lower than those in the control group(t=6.75,8.37,2.74,9.65,5.73,4.04,P<0.05).The treatment effective rate of the observation group was higher than that of the control group(χ^(2)=4.44,P<0.05).Conclusion Transcendental meditation training combined with grain moxibustion in treatment of patients with mild to moderate postpartum depression can improve the serum levels of 5-HT,DA,E2 and LH,relieve depression,and improve sleep quality and clinical efficacy.