摘要
随着对脑内独特的免疫微环境的认识和了解的不断增加,免疫治疗已经成为治疗脑转移瘤的一种新的、有前景的治疗方案。放疗与免疫治疗具有协同作用,深入了解其在乳腺癌脑转移瘤中的作用机制,对指导乳腺癌脑转移瘤的治疗具有重要价值。目前免疫检查点抑制剂联合放疗在乳腺癌脑转移瘤的研究正在积极开展,为乳腺癌脑转移瘤患者带来了新的希望。
With the increasing understanding of the unique tumor microenvironment in the brain,immunotherapy have emerged as a new and promising treatment for brain metastases.Radiotherapy and immunotherapy have a synergistic effect,and it is of great value to understand its mechanism in the treatment of breast cancer brain metastases.At present,the study of immune checkpoint inhibitors combined with radiotherapy in breast cancer brain metastases is being actively carried out,bringing new hope to patients with breast cancer brain metastases.
作者
孙晓琳
张展昱
许林宗
刘英超
李晓梅
Sun Xiaolin;Zhang Zhanyu;Xu Linzong;Liu Yingchao;Li Xiaomei(Tumor Research and Therapy Center,Shandong Provincial Hospital,Cheeloo College of Medicine,Shandong University,Jinan 250021,China;Department of Neurosurgery,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)
出处
《国际肿瘤学杂志》
CAS
2022年第4期243-246,共4页
Journal of International Oncology
关键词
乳腺肿瘤
脑转移
免疫检查点抑制剂
放射治疗
Breast neoplasms
Brain metastases
Immune checkpoint inhibitors
Radiotherapy