摘要
缺血性脑血管病(ischemic cerebrovascular disease, ICVD)是常见的中枢神经系统疾病,具有较高的发病率和死亡率。脑侧支循环对常由动脉粥样硬化所致的ICVD具有良好的代偿作用。近年来有研究显示,miRNA在脑血管动脉粥样硬化及其侧支循环建立的多种生理、病理过程中发挥重要作用,具有作为ICVD疾病诊断和病情评估的新型生物标志物的潜力。本文就miRNA与ICVD脑血管动脉粥样硬化及其侧支循环建立的相关性作一综述。
Ischemic cerebrovascular disease(ICVD) is a common central nervous system disease with high morbidity and mortality. Cerebral collateral circulation has a positive compensatory effect on ICVD, which is often caused by atherosclerosis. In recent studies, various physiological and pathological processes of cerebrovascular atherosclerosis and establishment of collateral circulation were closely related to miRNA that has the potential to be used as a new biomarker for diagnosis and evaluation of ICVD. This article reviews the relationship between miRNA and cerebrovascular atherosclerosis, and the establishment of collateral circulation in ICVD.
作者
梁紫君
张雪儿
黄健
张林杰
安红伟
LIANG Zijun;ZHANG Xueer;HUANG Jian;ZAHGN Linjie;AN Hongwei(Department of Neurology,Liuzhou Traditional Chinese Medical Hospital,Liuzhou 545001,China;Graduate School,Guangxi University of Chinese Medicine,Nanning 530000)
出处
《中国比较医学杂志》
CAS
北大核心
2022年第5期132-137,共6页
Chinese Journal of Comparative Medicine
基金
广西重点研发计划(桂科AB16380233)
广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z20180391)
柳州市科技计划项目(2019BJ10611)
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210522)
广西中医药大学研究生教育创新计划项目(YCXJ2021127)。
