某妇女儿童医院临床药师对新生儿科不合理肠外营养医嘱的干预对策分析

Intervention Countermeasures of Clinical Pharmacists for Irrational Parenteral Nutrition Medical Orders in Neonatology of a Women and Children’s Hospital

目的:通过分析我院临床药师对新生儿科不合理肠外营养医嘱的干预对策,探讨安全有效的肠外营养干预措施。方法:回顾性分析2016-2018年我院新生儿科3869例患儿的肠外营养医嘱,统计不合理医嘱数量、比例,根据是否进行临床药师干预,将3869例患儿分为干预前组与干预组,比较两组患儿不合理用药情况。结果:干预后,不合理用药发生率较干预前下降,差异有统计学意义(P<0.05);新生儿住院时间以及住院费用较干预前减少,差异有统计学意义(P<0.05);新生儿肠外营养相关的不良反应发生率较干预前下降,差异有统计学意义(P<0.05)。结论:通过临床药师的干预,降低了新生儿科不合理肠外营养的发生率,保障了新生儿静脉用药的安全性及有效性。

Objective:To explore the safe and effective intervention countermeasures of parenteral nutrition by analyzing the intervention countermeasures of clinical pharmacists for irrational parenteral nutrition medical orders in neonatology of our hospital.Methods:Retrospective analysis of parenteral nutrition medical orders of 3,869 children in neonatology of our hospital from 2016 to 2018 was performed,and the number and proportion of irrational medical orders were statistically analyzed.According to the intervention of clinical pharmacists,3,869 children were divided into pre-intervention group and intervention group.Irrational drug use was compared between two groups.Results:After intervention,the incidence of irrational drug use decreased compared with before intervention,the difference was statistically significant(P<0.05).The length of stay and hospitalization cost of neonates decreased compared with before intervention,the differences were statistically significant(P<0.05).The incidence of parenteral nutrition-related adverse drug reactions in neonates decreased compared with before intervention,the difference was statistically significant(P<0.05).Conclusion:The intervention of clinical pharmacists can reduce the incidence of irrational parenteral nutrition in neonatology and ensure the safety and effectiveness of intravenous drug use in neonates.