摘要
闭塞性细支气管炎(bronchiolitic obsliterans,BO)是一种临床少见的慢性阻塞性肺疾病。儿童期主要以感染后闭塞性细支气管炎(post-infectious bronchiolitic obsliterans,PIBO)多见,病原包括腺病毒、肺炎支原体、流感病毒、副流感病毒、水痘病毒等,其中腺病毒最多见,占比>50%,此外也有百日咳感染引起BO的报道[1]。BO主要组织病理学改变为缩窄性细支气管炎,最终发展为持续性的严重气道受阻,临床上表现为反复持续咳嗽、喘息、进行性呼吸困难,体征常可见三凹征、哮鸣音及桶状胸等.
作者
刘霞(综述)
李渠北(审校)
Liu Xia;Li Qubei(Children’s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,National Clinical Research Center for Child Health and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)
出处
《儿科药学杂志》
CAS
2022年第6期63-64,I0001,共3页
Journal of Pediatric Pharmacy
