希氏束起搏在心力衰竭患者中的应用研究进展

Application progress of His bundle pacing in patients with heart failure

常规的右心室起搏位点为右心室的间隔及心尖部,而这并非生理性的起搏位点,可导致心室收缩非同步,进而引发起搏介导的心肌病,并使心力衰竭(简称心衰)患者的住院率升高。希氏束起搏模拟了正常心室的电激动顺序,是一种生理性起搏方式。近年来,希氏束起搏在心衰患者中的临床应用逐年增多,在临床实践中获益显著,是目前研究的热点。本文将从希氏束的解剖、电生理等方面,对希氏束起搏的研究现状及其在心衰患者中的应用进展进行综述。

The conventional pacing sites of right ventricular pacing are the right ventricular septum and apex.However,they are not physiological pacing sites,which could lead to asynchronous ventricular contraction,and further pacemaker-induced cardiomyopathy and increased hospitalization rate of patients with heart failure.His bundle pacing(HBP)simulates the electrical activation sequence of the normal ventricle,and is a physiological mode of pacing.In recent years,the clinical applications of HBP in patients with heart failure are increasing year by year.Moreover,HBP yields significant benefits in clinical practice,and becomes a hot topic of research at present.From the aspects including the anatomy and electrophysiology of His bundle,this paper reviews the research status of HBP and its progress applied in patients with heart failure.