同期放化疗鼻咽癌患者的集束化营养管理

Nutrition management bundles for nasopharyngeal carcinoma patients undergoing concurrent radiotherapy and chemotherapy

目的探讨同期放化疗鼻咽癌患者行集束化营养管理的效果。方法便利选取接受同期放化疗的初治鼻咽癌患者134例,将患者随机分为对照组(66例)和观察组(68例)。对照组行常规营养管理;观察组行集束化营养管理,包括营养知识教育、营养评估筛查、保证营养摄入、治疗相关症状的预防及处理、康复运动指导、心理支持。干预前后评价两组营养摄入达标情况、营养不良与疗程延后发生率,体重指数、血红蛋白、血清白蛋白和前白蛋白值。结果干预后,观察组营养不良与疗程延后发生率显著低于对照组,体重指数、白蛋白、血红蛋白、前白蛋白、75%能量摄入达标率和75%蛋白质摄入达标率显著高于对照组(P<0.05,P<0.01)。结论集束化营养干预可显著改善同期放化疗鼻咽癌患者营养状况,降低患者营养不良发生率。

Objective To explore the effect of nutrition management bundles for nasopharyngeal carcinoma(NPC)patients undergoing concurrent radiotherapy and chemotherapy.Methods A total of 134 NPC patients undergoing initial treatment of concurrent radiotherapy and chemotherapy were conveniently selected and randomized into a control group(n=66)and an experimental group(n=68).The control group was given routine nutrition management,while the experimental group received nutrition management bundles,which consisted of nutrition education,nutrition screening,ensuring nutrition intake,prevention and management of therapy-related symptoms,rehabilitation exercise guidance and psychological support.The standard reaching rate of nutrition intake,the incidence of malnutrition and delayed course of treatment,Body Mass Index(BMI),hemoglobin,serum albumin and serum prealbumin between the two groups before and after the intervention were assessed and compared.Results After the intervention,the incidences of malnutrition and delayed course of treatment in the experimental group were significantly lower than those in the control group,while its BMI,hemoglobin,serum albumin,serum prealbumin,the standard reaching rate of 75%energy intake and 75%protein intake were significantly higher than those of the control group(P<0.05,P<0.01).Conclusion The nutrition care bundles can significantly improve the nutritional status of NPC patients undergoing concurrent radiotherapy and chemotherapy,and reduce their incidence of malnutrition.