宣肺视角下脱发炎性因子的表达改变

Expression Changes of Inflammatory Factors in Alopecia from the Perspective of Xuanfei

脂溢性脱发(AGA)为临床常见疾病,病因复杂,且反复发病。目前多认为AGA与毛囊局部微炎症有关,IL-1、IL-6、细胞刺激因子等炎性因子可诱导脱发的发生。中医学家认为可从肺论治肌表感邪导致肺气失宣而引起的脱发,通过宣通肺气,发汗解表可达到祛邪外出的目的。因此,在补益气血基础上加予宣肺发汗治疗可有奇效。而现已有麻黄、黄芩、桑叶等诸多中药可抑制炎性因子的不良作用,宣发肺气。故文章分别在炎性因子在脱发中的作用和宣肺方法在脱发中的使用来进行综述。

Seborrheic alopecia(AGA)is a common clinical disease with complex etiology and recurrent disease.At present,it is generally believed that AGA is related to the local micro inflammation of hair follicle,and inflammatory factors such as IL-1,IL-6 and cytokines can induce hair loss.Traditional Chinese medicine experts believe that the treatment can be based on the lung,and the loss of hair can be caused by the loss of lung qi caused by the sense of pathogenic factors on the surface of muscles.The purpose of expelling pathogenic factors can be achieved through the promotion of lung qi,sweating and resolving the surface.Therefore,on the basis of invigorating qi and blood,the treatment of dispersing lung qi and sweating can be effective.At present,there are many traditional Chinese medicines,such as ephedra,Scutellaria,mulberry leaf,which can inhibit the negative effects of inflammatory factors and promote lung qi.Therefore,this paper reviewed the role of inflammatory factors in hair loss and the use of dispersing lung qi method in hair loss.