轻比重罗哌卡因与舒芬太尼在剖宫产手术腰麻中的效果

The Effect of Light Specific Gravity Ropivacaine and Sufentanil in Spinal Anesthesia During Cesarean Section

目的探讨轻比重罗哌卡因与舒芬太尼在剖宫产手术腰麻中的麻醉效果及其对应激反应的作用。方法随机选取本院84例剖宫产手术患者,选取时间2019年1月—2020年6月,采用随机数字表法分组,对照组(n=42)实施轻比重罗哌卡因麻醉,观察组(n=42)采取轻比重罗哌卡因联合舒芬太尼麻醉,对两组麻醉效果进行比较。结果血浆谷氨酸(glutamic acid,GLU)、儿茶酚胺(catecholamine,CA)和皮质醇(cortisol hormone,COR),麻醉后观察组更低,与对照组相比差异有统计学意义(P<0.05);观察组术后VAS评分比对照组低,麻醉起效时间、运动恢复时间比对照组早,而镇痛维持时间较对照组长,差异有统计学意义(P<0.05)。不良反应总发生率方面,两组差异无统计学意义(P>0.05)。麻醉15 min时,心率(heart rate,HR)、舒张压(diastolic blood pressure,DBP)及收缩压(systolic blood pressure,SBP)方面,观察组比对照组低(P<0.05)。结论轻比重罗哌卡因联合舒芬太尼在剖宫产手术患者腰麻中具有显著应用效果,不仅能够延长药物镇痛时间,同时能够加快运动恢复时间。

Objective To investigate the anesthetic effect of light specific gravity ropivacaine and sufentanil in spinal anesthesia for cesarean section and its effect on stress response.Methods A total of 84 patients with cesarean section in our hospital were randomly selected from January 2019 to June 2020.They were divided into 2 groups by random number table method.The control group(n=42)was anesthetized with light specific gravity ropivacaine and the observation group(n=42)was anesthetized with light specific gravity ropivacaine combined with sufentanil.The anesthetic effects of the two groups were compared.Results The levels of plasma glutamic acid(Glu),catecholamine(CA)and cortisol(COR)in the observation group were lower than those in the control group(P<0.05).The VAS score of the observation group was lower than that of the control group,the onset time of anesthesia and exercise recovery time were earlier than those of the control group,and the maintenance time of analgesia was longer than that of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Heart rate(HR),diastolic blood pressure(DBP)and systolic blood pressure(SBP)in the observation group were lower than those in the control group(P<0.05).Conclusion Light specific gravity ropivacaine combined with sufentanil has a significant effect in spinal anesthesia in patients undergoing cesarean section.It can not only prolong the time of drug analgesia,but also accelerate the time of exercise recovery.