人参活性成分及制剂在心血管疾病中的研究进展

Research progress of active ingredients and preparations of Panax ginseng in cardiovascular diseases

人参作为传统中药,治疗心血管疾病历史悠久,其活性成分主要包括人参皂苷、人参挥发油、人参多糖等,现代实验研究证实其具有抗心肌缺血再灌注损伤、抑制心肌纤维化、抗动脉粥样硬化、抗心律失常等功效,以人参为主要成分的复方制剂在临床也广泛用于治疗心力衰竭、心律失常、不稳定性心绞痛等疾病。文章通过对人参活性成分及制剂在心血管疾病领域的应用归纳整理,为临床应用人参及新药研发提供思路。

As a traditional Chinese medicine,Panax ginseng(人参)has a long history in the treatment of cardiovascular diseases,and its active ingredients mainly include ginsenosides,ginseng volatile oil,ginseng polysaccharides and so on.Modern experimental studies have confirmed that ginseng has the effects of anti-myocardial ischemia-reperfusion injury,inhibition of myocardial fibrosis,anti-atherosclerosis,anti-arrhythmia and so on.The compound preparation with ginseng as the main ingredient is also widely used in clinical treatment of heart failure,arrhythmia,unstable angina pectoris and other diseases.This paper summarizes the application of ginseng active ingredients and preparations in the field of cardiovascular disease,in order to provide ideas for clinical application of ginseng and new drug research and development.