鼻黏膜温度变化与鼻气流感知之间的相关性研究进展

Correlation between nasal mucosal temperature change and nasal airflow perception

关于鼻气流感知的机制仍知之甚少,目前认为产生鼻腔通畅感的主要机制是激活鼻黏膜温度感受器瞬态受体电位M型家族成员8。计算流体力学研究表明,鼻腔增加的热流量与患者主观气流感知相关。同样,使用温度探头对鼻腔进行的物理测量显示较低的鼻黏膜温度与更好的气流感知之间存在相关性。三叉神经功能检测也间接证实了这一点。本研究旨在综述鼻黏膜温度变化在鼻腔通畅感知中的作用及其量化方法。

The mechanism of nasal airflow perception remains little known.It is currently believed that the main mechanism for perceiving nasal patency is to activate transient receptor potential melastatin subtype 8.Computer fluent dynamics show that increased airflow and heat flux are associated with higher subjective scores.Similarly,physical measurements of the nasal cavity using a temperature probe show a correlation between the lower nasal mucosa temperature and better results.Trigeminal function detection also indirectly confirms this.This literature review aimed to explore the role of nasal mucosal temperature change in the subjective perception of nasal patency and the secondary aim was to appraise the relevant evidence about the mechanism.