介入治疗对Cockett综合征合并左下肢深静脉血栓临床疗效及对不良反应与生活质量的影响

Clinical Effect of Interventional Therapy on Cockett Syndrome Complicated with Left Lower Extremity Deep Venous Thrombosis and Its Influence on Adverse Reactions and Quality of Life

目的探讨介入治疗在Cockett综合征合并左下肢深静脉血栓(LEDVT)中的应用价值。方法回顾性分析2019年4月至2020年4月收治的86例Cockett综合征伴左LEDVT患者,依据治疗方案的不同分为对照组与观察组,均为43例,对照组采用外周系统溶栓治疗,观察组则实施介入治疗,对比两组患者的临床疗效、下肢静脉功能临床严重程度评分(VCSS)、不良反应、下肢深静脉血栓后遗症(PTS)以及生活质量[健康调查简表(SF-36)评分]。结果观察组的治疗有效率(97.67%)明显高于对照组(83.72%),且差异显著(P<0.05);经过治疗后,观察组的VCSS评分明显低于对照组(P<0.01);两组不良反应发生率对比并无明显差异(P>0.05),但观察组的PTS发生率明显低于对照组(P<0.05);此外,观察组在治疗后的SF-36评分明显高于对照组(P<0.05)。结论介入治疗对Cockett综合征伴左LEDVT患者具有显著的临床疗效,可有效改善患者的下肢静脉功能,降低其PTS的发生风险,对其生活质量的提升具有积极的应用价值。

Objective To investigate the application value of interventional therapy in Cockett syndrome complicated with left lower extremity deep venous thrombosis(LEDVT).Methods 86 cases of Cockett syndrome with left LEDVT admitted from April 2019 to April 2020 were retrospectively analyzed.According to the different treatment schemes,they were divided into control group and observation group,43 cases in each group.The control group was treated with peripheral thrombolysis,while the observation group was treated with interventional therapy.The clinical efficacy,lower extremity venous function venous clinical severity score(VCSS)and blood pressure adverse reactions,deep venous thrombosis sequelae(PTS)and quality of lifeof the two groups were compared[SF-36 score].Results The effective rate of the observation group(97.67%)was significantly higher than that of the control group(83.72%),and the difference was significant(P<0.05);After treatment,the VCSS score of the observation group was significantly lower than that of the control group(P<0.01);There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05),but the incidence of PTS in the observation group was significantly lower than that in the control group(P<0.05).In addition,the SF-36 score of the observation group after treatment was significantly higher than that of the control group(P<0.05).Conclusion Interventional therapy has significant clinical effect on Cockett syndrome with left LEDVT,which can effectively improve the venous function of lower limbs,reduce the risk of PTS,and has positive application value for improving the quality of life.