普米克令舒治疗小儿哮喘急性发作的效果评价及对肺功能的影响

Effect of Pulmicrine on Acute Asthma in Children and Its Effect on Lung Function

目的探讨普米克令舒治疗小儿哮喘急性发作的效果及对肺功能的影响。方法选取我院于2018年2月至2019年9月收治的77例哮喘急性发作的患儿作为研究对象,按不同治疗方式进行分组。对照组采用常规对症治疗,观察组采用氧驱雾化吸入普米克令舒治疗,对比两组患儿的治疗效果,观察不同疗法患儿的第1秒用力呼气容积、用力肺活量、最大呼气峰值流量。结果治疗前,两组患儿第1秒用力呼气容积、用力肺活量、最大呼气峰值流量对比,差异无统计学意义,P>0.05。治疗后,两组患儿呼气容积、用力肺活量、最大呼气峰值流量均较治疗前改善,且观察组的呼气容积、用力肺活量、最大呼气峰值流量显著高于对照组,差异有统计学意义,P<0.05。对照组显效11例(占42.31%)、有效9例(占34.62%)、无效6例(占23.08%),总有效率为76.92(20/26);观察组显效33例(占64.71%)、有效15例(占29.41%)、无效3例(占5.88%),总有效率为94.12(48/51)。观察组总有效率高于对照组,差异有统计学意义,P<0.05。治疗后,观察组患儿咳嗽、气促、哮鸣音症状缓解时间均短于对照组,差异有统计学意义,P<0.01。结论对于小儿哮喘急性发作,在常规对症治疗的基础上应用普米克令舒氧驱雾化吸收治疗能快速改善患儿的临床症状及肺功能,确保患儿健康生长发育。

Objective To investigate the effect of pulmicort rexide on acute attack of asthma in children and its effect on lung function.Methods A total of 77 children with acute asthma attacks who were admitted to our hospital from February 2018 to September 2019 were selected as the research subjects,and were grouped according to different treatment methods.The control group was given routine symptomatic treatment,the observation group was given oxygen-driven nebulization and inhalation of pulmicorin.The therapeutic effects of the two groups of children were compared,and the forced expiratory volume in 1 second,the forced vital capacity and the maximum expiratory peak flow of the children with different treatments were observed.Results There were no significant differences in forced expiratory volume,forced vital capacity and maximum expiratory peak flow 1 second before treatment between the two groups(P>0.05).After treatment,the expiratory volume,forced vital capacity and peak expiratory flow of the two groups of children were all improved compared with those before treatment,and the expiratory volume,forced vital capacity and peak expiratory flow of the observation group were significantly higher than those of the control group,the difference was statistically significant,P<0.05.The indexes of expiratory volume,forced vital capacity and maximum expiratory peak flow in the observation group after treatment were significantly higher than those in the control group after conventional treatment,P<0.05.In the observation group,there were 11 cases(42.31%)of marked effect,9 cases(34.62%)of effective,6 cases(23.08%)of ineffective,the total effective rate was 76.92%(20/26).In the observation group,there were 33 cases(64.71%)of marked effect,15 cases(29.41%)of effective,3 cases(5.88%)of ineffective.The total effective rate was 94.12%(48/51),and the difference was significant,P<0.05.After symptomatic treatment in different ways,there was significant difference in the relief time of cough,shortness of breath and wheezing between the two groups,and the difference was significant,P<0.01.Conclusion For children with acute asthma attack,on the basis of conventional symptomatic treatment,the application of atomization absorption of pulmicoride oxygenation can quickly improve the clinical symptoms and lung function of children,ensure the healthy growth and development of children.