计算机化认知行为疗法对老年轻度认知功能障碍患者抑郁焦虑的影响

Effect of computerized cognitive behavior therapy on depression and anxiety in elderly patients with mild cognitive impairment

目的:探讨计算机化认知行为疗法(CCBT)对老年轻度认知功能障碍(MCI)患者焦虑、抑郁的影响。方法:选取2019年10月至2020年12月就诊于浙江省立同德医院的MCI老年患者60例,采用随机数字表法分为观察组和试验组,每组30例。观察组给予基础对症治疗,试验组加用CCBT进行干预,时间为1月,干预前、干预后(CCBT治疗后即时)和干预后1个月分别对两组患者采用焦虑自评量表(SAS)和抑郁自评量表(SDS)进行评分。结果:干预后两组患者的SAS评分均较干预前低(P<0.01),试验组评分明显低于对照组(P<0.01)。干预后1月两组患者SAS评分均较干预后升高,且试验组评分低于对照组(P<0.01)。干预后两组患者的SDS评分均较干预前降低(P<0.01)。结论:CCBT可改善老年MCI患者的焦虑抑郁情况,特别是对焦虑症状有显著效果。

Objective: To evaluate the effect of computerized cognitive behavior therapy(CCBT) on anxiety and depression in elderly patients with mild cognitive impairment(MCI). Methods: Sixty elderly patients with MCI in Tongde Hospital of Zhejiang Province from October 2019 to December 2020 were analyzed retrospectively. Patients were randomly assigned into two groups with 30 cases in each group. Patients in control group were given basic symptomatic treatment, and those in the trial group were given CCBT intervention for one month. Self-rating anxiety scale(SAS) and self-rating depression scale(SDS) were used to score the two groups before intervention, immediately after intervention, and one month after intervention. Results: After the intervention, the SAS scores of the two groups were lower than those before intervention(P<0. 01), and the scores of the trial group were significantly lower than those of the control group(P<0. 01). One month after intervention, the SAS scores of the two groups were higher than those immediately after intervention, and the scores of the trial group were lower than those of the control group(P<0. 01). SDS scores of the two groups after intervention were lower than those before intervention(P<0. 01). Conclusion: CCBT can improve the anxiety and depression in elderly patients with MCI, especially for anxiety.