多因素logistic回归分析眶下间隙感染的影响因素及五水头孢唑林钠的干预效果研究

logistic Analysis of Multiple Factors Affecting Infraorbital Space Infection and the Intervention Effect of Cefazolin Pentahydrate Sodium

目的:探讨多因素logistic回归分析眶下间隙感染的影响因素及五水头孢唑林钠干预效果。方法:回顾性分析2018年5月-2021年2月庄河市中心医院口腔科收治的532例患者的临床资料,根据患者是否为眶下间隙感染分为感染组(n=47)和非感染组(n=485)。查阅医院的档案资料,记录两组性别、年龄、侵入性操作、高血压史、糖尿病史、预防性抗生素使用、低蛋白血症、体重指数(BMI)、误吸等情况,并进行单因素及多因素logistic回归分析。按照治疗方法将感染组患者分为观察组(n=25)和对照组(n=22),对照组采用头孢唑林钠治疗,观察组采用五水头孢唑林钠干预,用药7 d后,比较两组干预效果。结果:532例口腔科患者参考眶下间隙感染标准最终确诊47例,确诊率为8.83%。单因素分析结果表明,感染组与非感染组患者的年龄、侵入性操作、预防性抗生素使用、低蛋白血症、误吸情况比较,差异均有统计学意义(P<0.05)。多因素logistic分析结果表明,年龄、侵入性操作、未预防性使用抗生素、低蛋白血症、误吸是发生眶下间隙感染的危险因素(P<0.05)。观察组给予五水头孢唑林钠干预后患者体温恢复、肿胀消失、住院时间、疼痛消失时间均短于对照组,差异均有统计学意义(P<0.05)。结论:口腔科眶下间隙感染率较高,且受到的影响因素较多,且不同因素能相互作用及影响,给予患者五水头孢唑林钠干预能缩短患者恢复时间。

Objective:To explore the multivariate logistic analysis of infection in infraorbital space and the intervention effect of Cefazolin Pentahydrate Sodium.Method:The clinical data of 532 patients admitted to the Department of stomatology,Zhuanghe City Central Hospital from May 2018 to February 2021 were retrospectively analyzed.According to whether the patients had suborbital space infection,they were divided into infection group (n=47) and non-infection group (n=485).The hospital archives were checked for gender,age,invasive procedures,history of hypertension,history of diabetes,prophylactic antibiotic use,hypoalbuminemia,body mass index (BMI),aspiration and other conditions of the two groups,and univariate and multivariate logistic analysis were performed.According to the treatment method,the patients in the infection group were divided into observation group (n=25) and control group (n=22).The control group was treated with Cefazolin Sodium,and the observation group was treated with Cefazolin Pentahydrate Sodium intervention.After 7 d of medication,the intervention effect of the two groups was compared.Result:532 dental patients,47 were finally diagnosed with reference to the standard of infraorbital space infection,with a diagnosis rate of 8.83%.Univariate analysis showed that there were statistically significant differences in age,invasive procedures,prophylactic antibiotic use,hypoproteinemia and aspiration between the infected group and the non-infected group (P<0.05).Multivariate logistic regression analysis showed that age,invasive procedures,no prophylactic use of antibiotics,hypoalbuminemia,and aspiration were risk factors for infraorbital space infection (P<0.05).After the intervention of Cefazolin Pentahydrate Sodium,the body temperature recovery,swelling disappearance,hospitalization time,and pain disappearance time in the observation group were shorter than those in the control group,the differences were statistically significant (P<0.05).Conclusion:The infraorbital space infection rate in stomatology department is high,and there are many influencing factors,and different factors can interact and influence each other,the intervention of Cefazolin Pentahydrate Sodium can shorten the recovery time of patients.