摘要
代谢综合征(Mets)是一系列心血管疾病的高危因素。碘营养状态的改变可直接介导胰岛素抵抗的发生,影响糖脂代谢及血压水平的调节,亦可通过调节甲状腺功能间接参与Mets的发病过程。探索碘在Mets发生发展中的作用,可为预防和治疗Mets提供新的思路。
Metabolic syndromes(Mets)is a high-risk factor for a series of cardiovascular diseases.Changes in iodine nutritional status can directly mediate the occurrence of insulin resistance,affect glucose and lipid metabolism and the regulation of blood pressure and also,may contribute to the pathogenesis of Mets by regulating thyroid function.Exploring the role of iodine in the occurrence and development of Mets can provide new ideas for the prevention and treatment of Mets.
作者
许晓双
闵行
叶月
郭梦然
甄东户
XU Xiao-shuang;MIN Hang;YE Yue;GUO Meng-ran;ZHEN Dong-hu(the First Clinical Medical College,Lanzhou University,Lanzhou 730030;Department of Endocrinology,the First Hospital of Lanzhou University,Lanzhou 730000,China)
出处
《基础医学与临床》
2022年第6期979-982,共4页
Basic and Clinical Medicine
基金
上海市医药卫生发展基金会糖尿病临床研究项目(1期10研究)
标准化代谢性疾病管理中心(MMC)专项研究基金(2018-mmczxjj-3)。
关键词
碘
代谢综合征
甲状腺激素
胰岛素抵抗
iodine
metabolic syndrome
thyroid hormone
insulin resistance
