大鼠冲击性脑创伤的太赫兹波成像检测

Terahertz Wave Imaging Detection of Blast-Induced Traumatic Brain Injury of Rats

冲击波造成的脑创伤是目前较常见的致死致残疾病之一,对冲击性脑损伤的检测与分类具有重要意义。基于连续太赫兹波成像系统,对不同程度冲击波致伤的大鼠脑组织进行了连续太赫兹波衰减全反射成像检测,并采用支持向量机(SVM)分类器对不同创伤程度的脑组织太赫兹波成像结果进行分类识别。结果表明,太赫兹波衰减全反射成像技术可以实现对轻度、中度冲击性脑创伤脑部组织的检测。通过SVM分类器对不同创伤程度的脑部组织成像结果进行分类识别,其分类识别准确率可以达到86.36%。太赫兹波成像技术有望实现对不同程度冲击性脑创伤的早期精确检测与诊断。

Traumatic brain injury(TBI)caused by shock waves is one of the most common fatal and disabling diseases,and thus the early detection and classification of blast-induced TBI(bTBI)have important clinical significance.In this paper,based on the continuous terahertz wave imaging system,the brain tissues of rats with different degrees of bTBI are detected by the continuous-wave terahertz attenuated total reflection(CW THz-ATR)imaging system,and the THz images of these brain tissues of different levels of trauma are classified and identified by the support vector machine(SVM).The imaging results show that the detection of brain tissues with mild and moderate bTBI can be realized by the THz-ATR imaging technology.Moreover,the identification and classification of THz images of different levels of trauma by SVM can achieve the accuracy of 86.36%.This suggests that THz imaging technology has great potential for the early and precise detection and diagnosis of different degrees of bTBI.