血水混合物浓度及留存时间对模拟木质异物CT表现的影响:体外实验观察

Impact of blood-saline mixture concentrations and retention time on CT manifestations of simulated wooden foreign body:An in vivo experiment

目的通过体外实验观察不同浓度血水混合物及留存时间对模拟木质异物CT表现的影响。方法将20根杉木条置入含全血比例为0%、25%、50%、75%与生理盐水(血水)混合物及100%全血试管中,分别对应阴性对照(NC)组、T25组、T50组、T75组及T100组,每组4个样本。将试管置于恒温水浴锅中采集CT图像,每6 h重复一次,共采集300 h;比较相同时间点各组最低密度区CT值、最高密度区CT值和低密度区体积差异,评价时间及血水混合物浓度对木质异物CT参数的影响及其交互作用。结果随时间延长,各组时间-最低密度区CT值曲线呈速升-缓升型,时间-最高密度区CT值曲线呈速升-平台型;NC组和T25组时间-低密度区体积曲线呈速降型,T50组、T75组及T100组时间-低密度区体积曲线呈缓降型。血水混合物浓度及时间均对木质异物最低密度区CT值、最高密度区CT值及低密度区体积存在影响(P均<0.05),且二者对最低密度区CT值和低密度区体积存在交互作用(P均<0.05)。结论血水混合物浓度及留存时间均影响木质异物CT表现。

Objective To observe the impact of different concentrations of blood-saline mixtures and retention time on CT manifestations of simulated wooden foreign bodies through in vivo experiment.Methods Twenty China fir strips were selected and placed into test tubes fulling with blood-saline mixture of different concentrations(whole blood ratio of 0%,25%,50%,75%and 100%),namely negative control(NC)group,T25 group,T50 group,T75 group and T100 group(each n=4).The tubes were placed in a thermostatic water bath.Acquisition of CT images was performed immediately and 6 h after modeling and repeated with an internal of 6 h to 300 h.CT values of the lowest density area,of the highest density area and the volume of the low density area of the strips were compared among groups at the same time points.The impact of retention time and concentrations of blood-saline mixture,as well as the interaction between them on CT manifestations of the simulated wooden foreign bodies were analyzed.Results With time going,CT value curves of time-lowest density area of the strips showed fast-rising to slow-rising type,of time-highest density area showed fast-rising platform type in all 5 groups.The time-volume of low density area curve in NC group and T25 group were fast-decreasing type,while of T50 group,T75 group and T100 group were slow-decreasing type.Both the concentration blood-saline mixture and the retention time affected CT values of the lowest and the highest density areas,as well as the volume of the low density area(all P<0.05),and an interaction effect was observed on CT value of the lowest density area and the volume of the low density area(both P<0.05).Conclusion Both the concentration of blood-saline mixture and retention time had impact on CT manifestations of simulated wooden foreign bodies in vivo.