六苯基氮杂氟硼二吡咯的合成探究和光谱测试

Synthesis and Spectrum of Hexaphenyl AzaBODIPY

从对十二烷氧基苯甲醛和对十二烷氧基苯乙酮原料出发,经过羟醛缩合、迈克尔加成、成环和氟硼络合四步反应合成了具有长烷基链的四苯基氮杂氟硼二吡咯,再经过溴化反应、Suzuki偶联得到六苯基氮杂氟硼二吡咯。还探究反应温度、反应时间和催化剂用量对Suzuki反应的影响,探索出最合适的反应条件。本研究可为相关六苯基氮杂氟硼二吡咯化合物的合成提供参考。

AzaBODIPY with long-chain group was synthesized starting from 4-dodecyloxybenzaldehyde and 4-dodecyloxyacetophenone through the four-steps of aldol reaction,michael addition,cyclization and complexation.After bromination,hexaphenyl BODIPY can be prepareded by Suzuki coupling.The different conditions of the Suzuki reaction were also tried to explore the effects of temperature,time and catalyst for optimal reaction conditions.This paper can provide a reference for the synthesis of related compounds.