非高密度脂蛋白胆固醇与心脑血管疾病的关系研究

Study on the Relationship Between Non-high Density Lipoprotein Cholesterol and Cardiovascular and Cerebrovascular Diseases

非高密度脂蛋白胆固醇(non-HDL-C)反映致动脉粥样硬化胆固醇的总量,而动脉粥样硬化是多种心脑血管疾病的基础,会进一步诱发心肌梗死、脑梗死。目前,non-HDL-C在冠状动脉粥样硬化性心脏病发病率、死亡率方面的预测价值已经得到证实,甚至优于传统的血脂指标。但是关于non-HDL-C和心脑血管疾病的相关研究较少,且已有研究存在争议。本文主要对non-HDL-C与心脑血管疾病的关系进行综述,以期为心脑血管疾病的诊治提供参考依据。

Non-high density lipoprotein cholesterol(non-HDL-C) reflects the total amount of atherosclerosis cholesterol,and atherosclerosis is the basis of a variety of cardiovascular and cerebrovascular diseases,which can further induce myocardial infarction and cerebral infarction.At present,the predictive value of non-HDL-C in the incidence and mortality of coronary atherosclerotic heart disease has been confirmed,even better than the traditional blood lipid index.However,there are few studies on non-HDL-C and cardiovascular and cerebrovascular diseases,and the existing studies are controversial.This article reviews the relationship between non-HDL-C and cardiovascular and cerebrovascular diseases,in order to provide reference for the diagnosis and treatment of cardiovascular and cerebrovascular diseases.