心肌梗死患者认知功能障碍的研究进展

Research progress of cognitive dysfunction in patients with myocardial infarction

冠心病是全球主要的死亡原因,急性心肌梗死是最常见的心血管疾病。心肌梗死与认知障碍之间可能存在相关性,但目前尚不清楚心肌梗死导致认知能力下降的确切机制。心肌梗死合并认知障碍对疾病的预后产生不良影响,且患者长期预后不容乐观可能与治疗不充分有关。随着人口老龄化和医疗干预手段的增加,需要制定具体策略来提高治疗效果。本文对心肌梗死患者认知障碍的发生机制,对终点事件的影响及治疗策略的研究进展进行综述。

Coronary heart disease(CHD)is a major cause of death in the world,and acute myocardial infarction is the most common cardiovascular disease.There may be a correlation between myocardial infarction and cognitive impairment,but the exact mechanism of cognitive decline remains unknown.Myocardial infarction with comorbid cognitive impairment negatively affects the prognosis,and the poor long-term prognosis may be associated to inadequate treatment.Population aging and increasing medical interventions necessitate specific strategies to improve therapeutic effect.This paper reviews the mechanism of cognitive impairment in patients with myocardial infarction,the influence of endpoint events and the research progress in treatment strategies.