2020年嘉兴市南湖区适龄妇女宫颈癌筛查结果分析

Analysis of cervical cancer screening results of age-appropriate women in Nanhu District, Jiaxing city, 2020

目的分析2020年嘉兴市南湖区适龄妇女宫颈癌筛查结果,了解该地区宫颈癌的发病情况和特点,为开展该地妇女健康保健工作提供依据。方法2020年7—8月在嘉兴市南湖区对适龄妇女进行宫颈癌筛查,筛查个案基本信息和筛查结果均录入浙江省两癌检查项目管理系统。结果共筛查22062例妇女,年龄30~64岁,平均(49.78±5.34)岁;检出高危HPV阳性者1646例,HPV感染率随年龄增加而增加,HPV平均感染率前3位分别为HPV52(226.92‱)、58(117.81‱)及56(86.94‱)。检出宫颈低级别鳞状上皮内病变(LSIL)74例,宫颈高级别鳞状上皮内病变(HSIL)14例,原位腺癌3例,鳞状细胞癌1例。不同年龄组(30~40岁、41~50岁、51~60岁、>60岁)LSIL在阳性人群中的检出率分别为36.46‰、41.87‰、43.48‰、61.72‰;HSIL在阳性人群中的检出率分别为10.42‰、12.32‰、6.21‰、8.23‰,差异均无统计学意义(χ^(2)=2.05、1.29,均P>0.05)。不同年龄组宫颈癌鳞检出率比较,差异无统计学意义(χ^(2)=1.05,P=0.79)。结论HPV52、58为该地区感染率最高的型别,该区域高危型HPV16、18、52及58的感染与高级别宫颈上皮内病变的发生显著相关,重视围绝经期HPV阳性妇女的管理,重点加强对该年龄段妇女的宣传,以降低宫颈癌患病率,保障妇女健康。

Objective To analyze the cervical cancer screening results of women of appropriate age in Nanhu District,Jiaxing city in 2020,to understand the incidence and characteristics of cervical cancer in this area,and to provide a basis for women's health care work in this area.Methods From July to August 2020,women of the right age in Nanhu District of Jiaxing City were selected for cervical cancer screening.The basic information and results of the screening cases were recorded into Zhejiang Provincial Cancer and Cancer Examination Project Management System.Results A total of 22062 cases were screened,aged from 30 to 64 years old,with an average of(49.78±5.34)years old.Among 1646 high-risk cases,HPV positive cases were detected,and the rate of HPV infection increased with age,with the average HPV infection rate ranking among the top three of HPV52(226.92 per 10000 children),58(117.81 per 10000 children),and 56(86.94 per 10000 children).74 cases of low grade cervical squamous intraepithelial lesions(LSIL),14 cases of high grade cervical squamous intraepithelial lesions(HSIL),3 cases of adenocarcinoma in situ,and 1 case of squamous cell carcinoma were detected.The detection rate of LSIL in different age groups(30-40 years old,41-50 years old,51-60 years old,>60 years old)were 36.46‰,41.87‰,43.48‰and 61.72‰,respectively.The detection rates of HSIL in the positive population were 10.42‰,12.32‰,6.21‰and 8.23‰,respectively,and there were no statistical significance(χ^(2)=2.05,1.29,P>0.05).There was no significant difference in the detection rate of cervical cancer among different age groups(χ^(2)=1.05,P=0.79).Conclusion HPV52 and HPV58 were the highest infection types in this region.The infection of high-risk types HPV16,18,52 and 58 in this region was significantly correlated with the occurrence of HSIL.Pay attention to the management of perimenopausal women with HPV positivity,and focus on strengthening the publicity of women in this age group,so as to reduce the incidence of cervical cancer and protect women's health.