植物花青素对肿瘤抑制作用的研究进展

Research progress in the inhibitory effects of plant anthocyanins on tumors

植物花青素是一类可溶于水的类黄酮,主要存在于各种蔬菜水果中。常见的植物花青素主要分为天竺葵色素(Pelargonidin)、芍药色素(Peonidin)、矢车菊色素(Cyanidin)、锦葵色素(Malvidin)、矮牵牛色素(Petunidin)、飞燕草色素(Delphinidin)六种;植物花青素分子中含有共轭双键体系,并含有碱性或酸性基团,因而具有抗氧化、抗炎、调节免疫、抗衰老和抑癌等生物学作用,尤其以抑癌作用最为突出。因此,本文将对植物花青素的抑癌作用及可能的机制进行综述。

Plant anthocyanins are a class of water-soluble flavonoids,which mainly found in various vegetables and fruits.Common plant anthocyanins are mainly divided into six species including pelargonidin,peonidin,cyanidin,malvidin,petunidin,and delphinidin;Because the phytocyanin molecules contain conjugated double bond systems with basic or acidic groups,they have biological effects such as anti-oxidation,anti-inflammation,immune regulation,anti-aging,and anti-cancer,especially for inhibitory effects of tumor.Therefore,this article will review tumor suppressive effects and possible mechanisms of plant anthocyanins.