乳腺浸润性微乳头状癌转移机制的研究进展

Research progress on the mechanism of metastasis in invasive micropapillary carcinoma of the breast

乳腺浸润性微乳头状癌(Invasive micropapillary carcinoma,IMPC)是一种罕见的乳腺癌组织病理学变异,约占所有乳腺癌的3%~8%。尽管IMPC的发病率较低,但与非特殊类型浸润性导管癌(Invasive ductal carcinoma of no special type,IDC-NST)相比,IMPC显示出更高的淋巴管浸润和淋巴结转移倾向。因此,了解其转移机制对于干预临床诊疗过程显得尤为重要。本文旨在综述IMPC的转移机制及相关临床证据,从而为IMPC的治疗提供新的思路。

Invasive micropapillary carcinoma(IMPC)of breast is a rare histopathological variant of breast cancer,accounting for approximately 3%-8%of all breast cancer.Compared with invasive ductal carcinoma of no special type(IDC-NST),although the incidence of IMPC is low,IMPC shows a tendency of lymphatic invasion and lymph node metastasis.Therefore,understanding its metastasis mechanism is particularly important for intervening in the clinical diagnosis and treatment process.This article aims to review the metastatic mechanism of IMPC and related to clinical evidence,so as to provide new ideas for the treatment of IMPC.