脑水肿患儿连续性血液净化应用策略

Application strategies of continuous blood purification in pediatric patients with cerebral edema

连续性血液净化(CBP)已广泛应用于儿童各种危重症的救治,对脑水肿疗效确切,但CBP自身可导致患儿血压、血容量、血浆渗透压、药物代谢等因素改变,若临床评估干预不够或治疗参数设置不当,势必会影响其疗效,甚至存在加重脑水肿风险。本文就合并脑水肿患儿进行CBP的应用策略进行综述,为临床提供参考。

Continuous blood purification(CBP)has been extensively used in pediatric critical care and proven effective in pediatric patients with cerebral edema.However,as a causative factor of changes in blood pressure,blood volume,plasma osmotic pressure,and drug metabolism,CBP may have reduced efficacy and even exacerbate the cerebral edema when pediatric patients are provided with inadequate clinical evaluation and intervention or inappropriate settings of treatment parameters.This paper presented a literature review on the application strategies of CBP as a treatment of pediatric patients with cerebral edema to provide a reference for clinical practice.