摘要
Herein, we presented a novel biodegradable copolymer via the chain extending reaction of poly(pdioxanone)-co-poly(2-(2-hydroxyethoxy) benzoate)(PPDO-co-PDHB) prepolymer with hexamethylene diisocyanate(HDI) as a chain extender. The structures and molecular weight of PPDO-co-PDHB prepolymer and PPDO-co-PDHB-PU chain-extended copolymer are characterized via hydrogen nuclear magnetic resonance spectroscopy(1 H NMR) and viscosity test. The relationship between the molecular structures and properties of the chain-extended copolymers is established. The PPDO-co-PDHB-PU copolymers possess a better thermal stability comparing with the PPDO homopolymer. The study of mechanical properties shows that the elongation-at-break of PPDO-co-PDHB-PU is much higher than that of PPDO. The investigation of hydrolytic degradation behaviors indicates the degradation rate of PPDO can be controlled by adjusting the PDHB compositions, and proves that chain-extended copolymers exhibit an excellent hydrolytic stability being better than that of PPDO.
基金
supported by the National Natural Science Foundation of China (No. U19A2095)
the Sichuan Science and Technology Program (No. 2017SZDZX0015)
the Fundamental Research Funds for the Central Universities。
