金华市某非综合性医院76例HIV/AIDS流行特征及WB带型分析

Epidemic characteristics of 76 HIV/AIDS cases and analysis of its Western blotting bands in a non-general hospital in Jinhua

目的 分析金华市某非综合性医院上报的艾滋病病毒感染者/艾滋病患者(HIV/AIDS)的流行特征,及蛋白质免疫印迹(WB)带型特征,为当地的艾滋病防控策略提供一定的科学依据。方法 收集本院2016年1月-2021年7月HIV抗体筛查阳性并送确证实验室WB确证为阳性病例的相关资料,采用描述性流行病学方法进行分析;对WB条带阳性率和带型分别进行汇总分析。结果 共报告新发HIV/AIDS 76例,男女性别比为3. 5∶1;以20岁~50岁为主;文化程度以小学到高中为主;前3位职业依次为务工人员、农民、工人;户籍以外省为主;未婚28例,已婚30例;传播途径以性传播为主,异性性传播占86. 64%;样本来源以住院患者为主。WB带型以3种带型为主,gp160、gp120、gp41和p24条带出现概率均为100. 00%,其他条带有不同程度的缺失。结论 本院HIV/AIDS以男性、低学历、青中年为主,传播途径以性传播为主,应进一步加强重点人群的相关知识宣传和教育,扩大重点人群的筛查,积极做好干预工作,对艾滋病防控具有重要意义。

Objective To analyze the epidemiological characteristics of HIV/AIDS cases and Western blotting band patterns in a non-general hospital in Jinhua,and to provide basis for disease control and prevention.Methods The epidemiological data of patients who showed HIV positive in our hospital and confirmed by Jinhua CDC from January 2016 to July 2021 were collected,and descriptive epidemiological analysis of them was carried out.WB band positive rates and patterns were analyzed separately.Results A total of 76 patients were confirmed to be HIV/AIDS.The proportion of men to women was 3.5:1.These patients mainly distributed in the population aged 20-50.The educational background distribution was primary school to senior high school mainly.The top three careers were migrant workers,farmers,and workers.These patients commonly came from other provinces.28 patients were unmarried,and 30 patients were married.Sexual transmission was the mostly common transmission ways,and 86.64%of patients were infected via heterosexual transmission.Most of these patients were found from inpatients.A total of 3 kinds of WB band patterns were the main bands.The bands of gpl60,gpl20,gp41,p24 were observed in all the patients(100.00%),and the other bands were missing to varying degrees.Conclusion The majority of HIV/AIDS in our hospital were male,low-educated and young and middle-aged.Sexual transmission was the mostly common transmission ways.Strengthening the related knowledge,education,the screening and intervention among high-risk population has great significance for AIDS prevention and control.