骨质疏松性椎体压缩骨折行PKP术后再骨折的影响因素

Influencing factors of re-fracture in osteoporotic vertebral compression fracture after percutaneous kyphoplasty

目的观察骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fracture,OVCF)患者接受PKP术后再骨折的影响因素。方法选取本院80例行PKP治疗的OVCF患者,按照术后是否再次骨折,分为再次骨折组与未骨折组,收集患者临床资料,采用Logistic回归模型分析术后再骨折的相关影响因素。结果术后共13例患者(17个椎体)再骨折,发生率16.25%;再次骨折组与未骨折组在年龄、骨折病史、骨水泥渗漏、BMD及椎体高度恢复率等方面的比较有统计学意义(P<0.05);75岁以上、骨折病史、骨水泥渗漏、低BMD、高椎体高度恢复率为术后再次骨折独立危险因素(P<0.05)。结论OVCF患者PKP术后具有较高的再骨折风险,且以单椎再骨折为主,年龄>75岁、骨折病史、骨水泥渗漏、低BMD、椎体高度恢复率属于其主要的独立危险因素。

Objective To observe the influencing factors of re-fracture in patients with osteoporotic vertebral compression fracture(OVCF)after percutaneous kyphoplasty(PKP).Methods Eighty patients with OVCF treated by PKP were selected,and the occurrence of re-fracture after surgery was analyzed.According to presence or absence of re-fracture,the patients were divided into re-fracture group and non-fracture group.The patients’clinical data were collected to analyze the influencing factors of re-fracture in patients with OVCF after PKP by Logistic regression model.Results After surgery,there were 13 patients(17 vertebraes)with re-fractures,with an incidence rate of 16.25%.The differences in age,fracture history,bone cement leakage,bone mineral density(BMD)and recovery rate of vertebral height between the re-fracture group and the non-fracture group were statistically significant(P<0.05).Over 75 years old,fracture history,bone cement leakage,low BMD and high recovery rate of vertebral height were independent risk factors of re-fracture(P<0.05).Conclusion Patients with OVCF have a higher risk of re-fracture after PKP,which mainly include single vertebral re-fracture.Over 75 years old,fracture history,bone cement leakage,low BMD and recovery rate of vertebral height are independent risk factors.