骨扫描指数自动程序在前列腺癌骨转移中的应用价值

The application value of automated bone scan index in bone metastasis of prostate cancer

前列腺癌(PCa)的发病率在男性肿瘤中位居首位,其易发生骨转移,主要表现为疼痛、生活质量降低、骨折、骨功能衰退、造血功能受损和生存率降低等。骨扫描指数(BSI)是一种定量测量骨病严重程度的方法,可以对PCa患者骨肿瘤的累及程度进行定量评估。将PCa治疗前后的骨显像变化与临床检查结果相结合,可以评估疾病的进展或缓解。笔者对BSI和BSI自动程序的发展及其在PCa方面的研究进行综述,以期为临床提供参考。

The incidence rate of prostate cancer(PCa)ranks first among all male tumors,and PCa is prone to bone metastasis,which is characterized by pain,decreased quality of life,fractures,bone functional decline,impairment of hematopoiesis,and reduced survival rate.Bone scan index(BSI)is a method to quantitatively measure the severity of bone diseases.It can not only quantitatively evaluate the degree of bone tumor involvement in PCa patients,but also incorporate fully quantitative assessments of disease burden in associating bone scintigraphy post-treatment changes with clinical examination outcome,to assess progression or remisson of disease.In this paper,BSI,the development of automated BSI and its research in PCa are reviewed to provide reference for clinical practice.