胃镜下病理活检和外科手术病理在胃癌评估中的应用分析

Application Analysis of Gastroscopic Pathological Biopsy and Surgical Pathology in Assessment of Gastric Cancer

目的:分析胃癌患者采用胃镜下病理活检和外科手术病理在胃癌评估中的临床价值。方法:选取2019年2月-2021年2月广西壮族自治区人民医院收治的胃癌患者共50例。分析胃镜下病理活检和外科手术病理在胃癌评估中的价值。结果:胃镜下病理活检和外科手术病理比较,差异无统计学意义(P>0.05)。外科手术病理印戒细胞癌、黏液腺癌检出率高于胃镜下病理活检,差异有统计学意义(P<0.05);两组管状腺癌和乳头状腺癌的检出率比较,差异无统计学意义(P>0.05)。两组诊断方法Ⅰ型诊断结果比较,差异无统计学意义(P>0.05);Ⅱ型、Ⅲ型、Ⅳ型胃镜活检诊断较低,差异有统计学意义(P<0.05)。外科手术病理分化不良型例数少于胃镜下病理活检,差异有统计学意义(P<0.05);外科手术病理分化型例数高于胃镜下病理活检,差异有统计学意义(P<0.05)。结论:胃镜下病理活检可作为术前诊断的良好手段,但对胃癌的全面评估,仍要以外科手术病理结果为依据。

Objective: To analyze the clinical value of gastroscopic pathological biopsy and surgical pathology in the assessment of gastric cancer in patients with gastric cancer. Methods: A total of 50 patients with gastric cancer admitted to the People’s Hospital of Guangxi Zhuang Autonomous Region from February 2019 to February 2021 were selected. The value of gastroscopic pathological biopsy and surgical pathology in the assessment of gastric cancer was analyzed. Results: There was no statistically significant difference between gastroscopic pathological biopsy and surgical pathology(P>0.05). The detection rate of signet ring cell carcinoma and mucinous adenocarcinoma by surgical pathology was higher than that by gastroscopic pathological biopsy, and the difference was statistically significant(P<0.05). There was no statistically significant difference in the detection rate of tubular adenocarcinoma and papillary adenocarcinoma between two groups(P>0.05). There was no statistically significant difference in the diagnosis result of type Ⅰ by the diagnosis methods between two groups(P>0.05);the diagnosis rate of type Ⅱ, type Ⅲ and type Ⅳ by gastroscopic biopsy was relatively low, and the difference was statistically significant(P<0.05). The number of patients with poorly differentiated type by surgical pathology was lower than that by gastroscopic pathological biopsy, with statistically significant differences(P<0.05);the number of patients with differentiated type by surgical pathology was higher than that by gastroscopic pathological biopsy, with statistically significant differences(P<0.05). Conclusion: Gastroscopic pathological biopsy can be used as a good tool for preoperative diagnosis, but the comprehensive assessment of gastric cancer should still be based on surgical pathological results.