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人免疫球蛋白与阿昔洛韦治疗病毒性脑膜炎疗效分析 被引量:1

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摘要 目的:探究人免疫球蛋白联合阿昔洛韦治疗病毒性脑膜炎的疗效及安全性。方法:将2018年1月至2020年1月接诊的120例病毒性脑膜炎患儿随机分为试验组与对照组,各60例。对比两组疗效及不良反应发生情况。结果:试验组总有效率高于对照组(P<0.05)。试验组头痛、高热及意识障碍等恢复时间均短于对照组(P<0.05)。试验组治疗后CD3^(+)、CD8^(+)水平高于对照组,CD4^(+)、血管内皮生长因子(VEGF)、基质金属蛋白酶-2(MMP-2)及降钙素基因相关肽(CGRP)水平均低于对照组(P<0.05)。试验组治疗后白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)水平均低于对照组(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:阿昔洛韦联合人免疫球蛋白治疗病毒性脑膜炎疗效理想,可提升患儿免疫力,抑制炎症反应,且安全性较好。
作者 师卫中
出处 《实用中西医结合临床》 2022年第7期46-48,63,共4页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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