逆境下植物MAPK级联途径基因的表达调控

Regulation of Gene Expression of Plant MAPK Cascade Pathway under Environmental Stresses

丝裂原活化蛋白激酶(mitogen-activated protein kinase,MAPK)级联反应途径,是植物重要的信号转导途径,与植物生长发育和逆境应答密切相关。本研究基于植物MAPK级联途径基因的分类、结构,综述了逆境下植物MAPK级联途径基因在转录水平、转录后水平和翻译后修饰水平上的表达调控,MAPK级联途径与乙烯、生长素、茉莉酸、脱落酸、磷脂等多种信号途径的交互作用,以及MAPK级联途径对下游特定转录因子的调控。以往对植物MAPK级联途径的研究主要聚焦于响应环境信号的MAPK级联的鉴定及级联途径基因的分离和功能分析上,近年来植物MAPK级联途径与其他信号途径的交互作用、MAPK级联途径基因的表达调控及其对下游转录因子的调控,逐渐成为全面揭示植物MAPK级联途径作用机制的重点。本综述为植物MAPK级联途径的透彻研究提供参考,为植物抗逆分子育种提供理论基础。

Mitogen-activated protein kinase(MAPK)cascade is an important signal transduction pathway in plants,which is closely related to plant growth and development and stress response.Based on the classification and structure of plant MAPK cascade pathway genes,the regulation of MAPK cascade pathway genes expression at the transcriptional,post-transcriptional and post-translational modification levels under stress,the cross-talking between MAPK cascade pathway and ethylene,auxin,jasmonic acid,abscisic acid and phospholipid signaling pathway,and the regulation of MAPK cascade pathway on downstream specific transcription factors were reviewed in this study.Previous studies on plant MAPK cascade pathways mainly focused on the identification of MAPK cascades in response to environmental signals and the isolation and functional analysis of cascade pathway genes.In recent years,the cross-talking between plant MAPK cascade pathway and other signal pathways,regulation of MAPK cascade pathway gene expression and its regulation of downstream transcription factors have gradually become the focus to fully reveal the mechanism of MAPK cascade pathway in plants.This paper is expected to provide reference for the thorough study on MAPK cascade pathway in plants,and provide a theoretical basis for molecular breeding of stress-resistant plants.