不同年龄层早发冠心病PCI术后不良事件及生存差异分析

Differences of Adverse Events and Survival Rates of Patients with Premature Coronary Artery Disease after PCI in Different Age Groups

目的探讨不同年龄层早发冠心病患者PCI治疗术后的不良事件及生存率差异。方法入选2015年01月至2017年01月就诊于西安交通大学第一附属医院心血管内科被诊断为早发冠心病的患者861例,按照年龄分18~40岁组、41~50岁组、51岁以上组,对比3组患者入院时的一般基线资料,临床特征及PCI术后5 a的不良事件发生率及生存率差异。结果不同年龄层危险因素存在一定统计学差异(P<0.05),在18~40岁和41~49岁组中,吸烟、饮酒的占比均高于51岁以上组,而51岁以上组糖尿病、高血压占比高于18~40岁和41~49岁组。3个年龄层患者PCI术后5 a的有效性终点事件和安全性终点事件以及生存概率差异均无统计学意义(P>0.05)。结论不同年龄层早发冠心病PCI术后5 a不良事件发生率及生存率无统计学差异,青年人群的早发冠心病更值得关注。

Objective To investigate the adverse events and survival rates differences of patients with premature coronary artery disease after PCI in different age groups.Methods The general and clinical data,incidence of adverse events and survival rates of 861 patients diagnosed with premature coronary artery disease from Jan 2015 to Jan 2017 in the Department of Cardiovascular Medicine of the First Affiliated Hospital of Xi’an Jiaotong University were obtained.We categorized the participants into three age groups(18~40 years,41~50 years and≥51 years)according to their age.Results Compared with the≥51 years group,the proportion of smoking,drinking were higher in the 18~40 years group and 41~49 years group,and the proportion of diabetes,hypertension were lower in the 18~40 years group and 41~49 years group.There were no statistically differences in the effectivity end points and safety end points among the three age groups(P>0.05).There was no significant statistical difference in 5-year survival after PCI among the three groups(P>0.05).Conclusion There is no statistical difference of the 5-year incidence of adverse events and survival rate in different age groups with premature coronary artery disease after PCI,and we should pay more attention to the young population once they are diagnosed with premature coronary arteryt disease.