儿童重症监护病房患儿抗菌药物应用评估和管理

Evaluation and management of application of antibiotics in PICU

抗菌药物是PICU使用最普遍的药物。对于重症感染患儿,合理的经验性初始抗菌药物使用,及时的评估和调整以及适当的抗菌治疗疗程对确保患儿疗效和减少抗菌药物滥用带来的不利影响至关重要。本文讨论了抗菌药物在临床应用中的几个主要问题,以提示PICU临床医生应加强对抗菌药物的评估和管理。

Antibiotics are the most commonly used medicines in PICU.For children with severe infection,it is very important to ensure the curative effect of patients and reduce the adverse effects of antibiotic abuse through reasonable empirical initial use of antibiotics,timely evaluation and regulation,and appropriate course of antibiotic treatment.This review discussed several main problems of clinical application of antibiotics in PICU,in order to help clinicians in PICU improve the evaluation and management of antibiotics use.