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核苷类似物联合用药治疗乙型肝炎的研究进展 被引量:1

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摘要 乙型肝炎病毒(HBV)感染在我国仍是常见的传染病之一,临床上使用的药物为HBV聚合酶抑制剂核苷类似物(NAs),但由于其产生耐药突变的不良反应,导致其疗效降低。本文归纳总结近些年在临床上新发现的NAs的耐药突变位点及联合用药的文献,以期为临床治疗HBV提供用药依据。
作者 马鑫娜
出处 《临床合理用药杂志》 2022年第16期177-181,共5页 Chinese Journal of Clinical Rational Drug Use
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  • 1Chinese Society of Hepatology and Chinese Society of Infectious Diseases,Chinese Medical Association. 42 Dongsi Xidajie,Beijing 100710,China.慢性乙型肝炎防治指南[J].中华肝脏病杂志,2005,13(12):881-891. 被引量:1931
  • 2Keeffe EB,Dieterich DT,Pawlotsky JM,et al.Chronic hepatitis B:preventing,detecting,and managing viral resistance.Clin Gastroenterol Hepatol,2008,6:268-274.
  • 3Yuen MF,Fung J,Wong DK,et al.Prevention and management of drug resistance for antihepatitis B treatment.Lancet Infect Dis,2009,9:256-264.
  • 4Lok AS,McMahon BJ.Chronic hepatitis B.Hepatology,2007,45:507-539.
  • 5Liaw YF,Leung N,Kao JH,et al.Asian-Pacific consensus statement on the management of chronic hepatitis B:a 2008 update.Hepatol Int,2008,2:263-283.
  • 6Locarnini S.Primary resistance,multidrug resistance,and crossresistance pathways in HBV as a consequence of treatment failure.Hepatol Int,2008,2:147-151.
  • 7European Association For The Study Of The Liver.EASL Clinical Practice Guidelines:management of chronic hepatitis B.J Hepatol,2009,50:227-242.
  • 8Liu F,Yu DM,Chen L,et al.Dynamic changes of hepatitis B virus quasispecies during early entecavir treatment in patients with different responses.APASL,2010:421.
  • 9Tenney DJ,Rose RE,Baldick CJ,et al.Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-na(i)ve patients is rare through 5 years of therapy.Hepatology,2009,49:1503-1514.
  • 10Carey I,Mendes A,Hughes S,et al.Efficacy and safety of Lamivudine plus Adefovir de novo combination therapy and Entecavir monotherapy in chronic Hepatitis B:A single centre clinical practice experience.2009,AASLD,502A.

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