针刀腰腹同调联合柳氮磺吡啶治疗强直性脊柱炎的疗效观察

Effect of akupotomye lumbar-abdominal simultaneous regulation combined with sulfasalazine on ankylosing spondylitis

目的探讨针刀腰腹同调联合柳氮磺吡啶治疗强直性脊柱炎(AS)的疗效。方法抽取2021年6月至2021年12月山西中医药大学附属医院收治的66例AS患者,采用随机数表法将其分为A组与B组,每组33例。B组采用柳氮磺吡啶治疗,A组在B组基础上采用针刀腰腹同调法治疗。观察两组疗效,并对两组治疗前、治疗2个月后疼痛程度[视觉模拟评分法(VAS)评分]、AS活动性指数评分[Bath强直性脊柱炎病情活动指数(BASDAI)评分]、AS功能指数评分[Bath强直性脊柱炎病情功能指数(BASFI)评分]、腰椎活动度(Schober试验)、指地距、枕墙距及血沉(ESR)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平进行比较。结果A组治疗总有效率为93.75%(30/32),高于B组的70.97%(22/31),P<0.05。治疗2个月后,两组VAS评分、BASDAI评分及BASFI评分均低于治疗前,且A组低于B组(P<0.05);两组腰椎活动度高于治疗前,指地距及枕墙距低于治疗前,且A组优于B组(P<0.05);两组ESR、血清CRP、TNF-α水平低于治疗前,且A组低于B组(P<0.05)。结论针刀腰腹同调治疗强直性脊柱炎疗效确切,可以改善患者脊柱功能,降低ESR和血清CRP水平。

Objective To investigate the effect of akupotomye lumbar-abdominal simultaneous regulation combined with sulfasalazine on ankylosing spondylitis(AS).Methods Sixty-six patients with AS admitted to Affiliated Hospital of Shanxi University of Traditional Chinese Medicine from June 2021 to December 2021 were selected and divided into group A and group B by random number table method,with 33 cases in each group.Patients in group B were treated with sulfasalazine,and patients in group A were treated by akupotomye lumbar-abdominal simultaneous regulation based on the treatment of group A.Curative effects of the two groups were observed.Pain level assessed by visual analogue scale(VAS)score,AS activity index assessed by Bath ankylosing spondylitis disease activity index(BASDAI)score,AS functional index assessed by Bath ankylosing spondylitis functional index(BASFI)score,range of motion of lumbar spine(Schober’s test),finger-to-ground distance,occipital-to-wall distance,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)levels were compared between the two groups before treatment and after 2 months of treatment.Results The total effective rate in group A(93.75%,30/32)was higher than that in group B(70.97%,22/31),P<0.05.After 2 months of treatment,the VAS score,BASDAI score and BASFI score of the two groups were lower than those before treatment,and those in the group A were lower than those in the group B(P<0.05).After 2 month of treatment,the range of motion of lumbar spine was higher than that before treatment,and the finger-to-ground distance and occipital-to-wall distance were shorter than those before treatment in the two groups(P<0.05)and those indexes in group A were better than those in group B(P<0.05).After 2 months of treatment,the serum ESR,CRP and TNF-αlevels in the two groups were less than those before treatment,and those in group A were lower than those in group B(P<0.05).Conclusions Akupotomye lumbar-abdominal simultaneous regulation is effective in the treatment of AS,which can improve the spinal function and reduce ESR and serum CRP levels in the patients.