极早发炎症性肠病1例

A case of very early onset inflammatory bowel disease

回顾性分析2018年10月广州市妇女儿童医疗中心消化科收治的1例极早发炎症性肠病(very early onset inflammatory bowel disease,VEO-IBD)患儿的临床资料。患儿女,因呼吸促、腹胀住院。胃肠道表现腹泻、黏液血便、喂养不耐受、体质量不增;肠外表现肝功能损害、关节损害。内镜检查考虑为VEO-IBD。予英夫利西单克隆抗体和肠内营养治疗。临床症状缓解,胃肠黏膜愈合后调整肠内营养方案,回归到日常饮食,体质量、身长达到正常儿童水平。炎症性肠病患者可合并各种肠外表现,临床医师需要识别这些疾病的共存现象,进行有效的随访。

The clinical data of a child with very early onset inflammatory bowel disease(VEO-IBD)treated in the digestive department of Guangzhou Women's and children's Medical Center in October 2018 were analyzed retrospectively.The patient was hospitalized because of"shortness of breath and abdominal distension"after birth.The gastrointestinal manifestations were diarrhea,mucus bloody stool,feeding intolerance and weight loss;the extraintestinal manifestations were liver function damage and joint damage.Endoscopic examination considered VEO-IBD.The patients were treated with infliximab and enteral nutrition.When the clinical symptoms were relieved and the gastrointestinal mucosa healed,the enteral nutrition regimen was adjusted.At present,she returned to daily diet,and the weight and height reached the level of normal children.VEO-IBD patients can be combined with a variety of extraintestinal manifestations,clinicians need to identify the coexistence of these diseases,effective follow-up.