静脉系统与脑小血管病白质高信号相关性研究

Study on relationship between venous system and white matter hyperintensitiy in cerebral small vessel disease

脑白质高信号是脑小血管病主要影像学标记物之一,普遍存在于老年人群中。目前其发病机制尚不清楚,以往的研究大多集中在动脉系统上,但静脉系统在脑白质高信号中的作用也越来越受到关注,小静脉胶原增生、下游颅内静脉扩张以及颈内静脉的返流或许都参与脑白质高信号的形成与发展。

White matter hyperintensity(WMH)is one of the major imaging markers of cerebral small vascular disease,which is prevalent in the elderly.At present,the pathogenesis of WMH is not clear,most of the previous studies focused on the arterial system,but the role of the venous system in WMH is attracting more and more attention.Small venous collagen hyperplasia,downstream intracranial venous dilatation and internal jugular venous reflux may be involved in the formation and development of white matter hyperintensity.