血液透析患者认知功能障碍的研究进展

Progress in Research of Cognitive Function in Hemodialysis Patients

血液透析治疗是慢性肾脏病终末期患者肾脏替代治疗的有效方法之一,被广泛应用于临床,但长期规律血液透析病程较长、发症较多、患者心理压力你和经济压力较大。其中认知功能障碍在长期规律血液透析患者中的发生率较高,而知晓率相对较低,严重影响患者的生活质量,降低患者治疗依从性,增加死亡风险。文章通过查阅大量文献并结合临床实际工作,对长期规律血液透析患者认知功能障碍的流行病学特征、发生的危害、相关影响因素(人口学因素、疾病相关因素、血液透析治疗相关因素、心理因素、尿毒症毒素因素)及干预措施等情况的研究进展进行分析、总结与综述,以期为相关研究与临床实际工作提供参考。

Hemodialysis is one of the effective methods of renal replacement therapy in end-stage patients with chronic kidney disease,However,long-term regular hemodialysis has a longer course,more symptoms,and greater psychological and economic pressure.The incidence of cognitive impairment in patients with long-term regular hemodialysis is high,but the awareness rate is relatively low,which seriously affects the quality of life of patients,reduce treatment compliance and increases the risk of death.In this paper,the epidemiological characteristics of cognitive dysfunction,the hazards,the related influencing factors(demographic factors,disease related factors,hemodialysis treatment related factors,psychological factors,uremic toxin factors)and the intervention measures of long-term regular hemodialysis patients were analyzed,summarized and summarized by consulting a large number of literature and combining with clinical practice.In order to provide reference for related research and clinical practice.