拉贝洛尔联合硫酸镁治疗重度子痫前期的效果

Effect of Labetalol combined with Magnesium Sulfate in the treatment of severe preeclampsia

目的探讨拉贝洛尔联合硫酸镁治疗重度子痫前期的效果。方法选取曲阜市人民医院2020年1月至2021年6月收治的80例重度子痫前患者为研究对象,采用随机数字表法分为两组,每组各40例。对照组开展硫酸镁治疗,观察组开展拉贝洛尔联合硫酸镁治疗。观察两组患者的血压水平、24 h尿蛋白、疗效、并发症、妊娠结局。结果治疗前两组患者的舒张压、收缩压、24 h尿蛋白比较,差异无统计学意义(P>0.05);治疗后观察组上述指标低于对照组,差异均有统计学意义(P<0.05)。观察组的总有效率高于对照组,并发症总发生率低于对照组,自然分娩率高于对照组,剖宫产率低于对照组,差异均有统计学意义(P<0.05)。结论采用拉贝洛尔联合硫酸镁治疗重度子痫前患者,能有效改善患者血压水平以及尿蛋白水平,降低并发症发生风险,改善妊娠结局,疗效显著。

Objective To investigate effect of Labetalol combined with Magnesium Sulfate in the treatment of severe preeclampsia.Methods A total of 80 patients with severe preeclampsia treated in Quf u People’s Hospital from January 2020 to June 2021 were selected as the research objects,using the method of random number table,the patients were divide into two groups,the control group(n=40)was treated with Magnesium Sulfate,and the observation group(n=40)was treated with Labeprolol combined with Magnesium Sulfate.Blood pressure,24 h urinary protein,curative effect,complications and pregnancy outcomes were observed in two groups.Results There were no significant differences in diastolic blood pressure,systolic blood pressure and 24 h urinary protein between the two groups before treatment(P>0.05).After treatment,the above indexes in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,the total incidence of complications was lower than that in the control group,the natural delivery rate was higher than that in the control group,and the cesarean section rate was lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion The use of Labeolol combined with Magnesium Sulfate in the treatment of severe preeclampsia patients can effectively improve the patients’blood pressure level and urinary protein level,reduce the risk of complications,improve pregna ncy outcomes,with significant efficacy.